Confidence bands for inverse regression models – with application to gel electrophoresis
نویسندگان
چکیده
We construct uniform confidence bands for the regression function in inverse, homoscedastic regression models with convolution-type operators. Here, the convolution is between two non-periodic functions on the whole real line rather than between two period functions on a compact interval, since the former situation arguably arises more often in applications. First, following Bickel and Rosenblatt [Ann. Statist. 1, 1071–1095] we construct asymptotic confidence bands which are based on strong approximations and on a limit theorem for the supremum of a stationary Gaussian process. Further, we propose bootstrap confidence bands based on the residual bootstrap. A simulation study shows that the bootstrap confidence bands perform reasonably well for moderate sample sizes. Finally, we apply our method to data from a gel electrophoresis experiment with genetically engineered neuronal receptor subunits incubated with rat brain extract.
منابع مشابه
Confidence bands for multivariate and time dependent inverse regression models
Uniform asymptotic confidence bands for a multivariate regression function in an in-verse regression model with a convolution-type operator are constructed. The results arederived using strong approximation methods and a limit theorem for the supremum of astationary Gaussian field over an increasing system of sets. As a particular applicationasymptotic confidence bands for a...
متن کاملDiversity of eukaryotic plankton of aquaculture ponds with Carassius auratus gibelio, using denaturing gradient gel electrophoresis
PCR-denaturing gradient gel electrophoresis (DGGE) and canonical correspondence analysis (CCA) were used to explore the relationship between eukaryotic plankton community succession and environmental factors in two aquaculture pond models with gibel carp Carassius auratus gibelio. The main culture species of pond 1 were gibel carp and grass carp, and the combined density was 46224 fingerling/ha...
متن کاملDiagnostic accuracy of an agarose gel electrophoretic method in multiple sclerosis.
To the Editor: In .95% of patients suffering from clinically unambiguous multiple sclerosis (MS), oligoclonal IgG can be detected in cerebrospinal fluid (CSF) (1, 2). Isoelectric focusing is the most sensitive method for detecting oligoclonal bands (OCBs) (1 ), whereas agarose gel electrophoresis is reported to detect OCBs in ;80% of cases (2 ). A commercial electrophoresis unit (Beckman Instru...
متن کاملUsing a Temperature Gradient against the Time in Polyacrylamide Gel Electrophoresis May Eliminate the Need for Stacking Gels
Background and Objectives: Making stacking gels for polyacrylamide gels in the laboratory by conventional methods is laborious and time consuming. Considering the role of temperature in polyacrylamide gels with respect to electrical resistance and viscosity, we assumed that decreasing the temperature would cause an increase in electrical resistance and viscosity. Ultimately, a downward tempera...
متن کاملHigh-contrast imaging of chlorophyll-containing protein complexes separated by native polyacrylamide gel electrophoresis
Electrophoregrams with bands of green chlorophyll-containing protein complexes separated by native polyacrylamide gel electrophoresis (PAGE) are usually photographed in white light or scanned by a narrow beam of monochromatic light using densitometers. Present CCD cameras allow taking densitograms of a whole gel surface with many samples. However, commercial CCD imaging systems use mostly white...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2008